Ali M, Ravinder E, Ramachandram R
Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India.
Pharmazie. 2000 May;55(5):385-9.
Phytochemical studies on the stem bark of Thevetia peruviana resulted in the isolation of six new ursane-type triterpenes, named peruvianursenyl acetate A, peruvianursenyl acetate B, isolupenyl acetate, peruvianursenyl acetate C, lupedienyl acetate and peruvianursenyl glucoside along with two known triterpenoids, namely alpha-amyrin acetate and lupeol acetate. The structures of the new phytoconstituents have been established as 23--nor methyl urs-12-en-4 alpha-ethylenic-18 alpha-H-3 beta-yl acetate, urs-5.21-dien-18 alpha-H-3 beta-yl acetate, lup-20 (29)-en-3 alpha-yl acetate, urs-12 en-18 alpha-H-3 beta-yl acetate, lup-5,20 (29)-dien-3 beta-yl acetate, and urs-12-en-18 alpha-H-3-O-beta-D-glucopyranoside, respectively.
对黄花夹竹桃茎皮进行的植物化学研究，分离出了六种新的乌苏烷型三萜，分别命名为秘鲁乌苏烯基乙酸酯A、秘鲁乌苏烯基乙酸酯B、异羽扇豆烯基乙酸酯、秘鲁乌苏烯基乙酸酯C、羽扇豆二烯基乙酸酯和秘鲁乌苏烯基葡萄糖苷，同时还分离出两种已知的三萜类化合物，即α-香树脂醇乙酸酯和羽扇豆醇乙酸酯。这些新植物成分的结构已分别确定为23-去甲基乌苏-12-烯-4α-亚乙基-18α-H-3β-基乙酸酯、乌苏-5,21-二烯-18α-H-3β-基乙酸酯、羽扇豆-20(29)-烯-3α-基乙酸酯、乌苏-12-烯-18α-H-3β-基乙酸酯、羽扇豆-5,20(29)-二烯-3β-基乙酸酯和乌苏-12-烯-18α-H-3-O-β-D-吡喃葡萄糖苷。
