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人类心肌细胞坏死与猝死。

Myocardial cell necrosis and sudden death in humans.

作者信息

Reichenbach D D, Moss N S

出版信息

Circulation. 1975 Dec;52(6 Suppl):III60-2.

PMID:1182983
Abstract

Using morphologic criteria to distinguish between myocardial infarction and lesions that selectively involve myocardial cells, the authors found evidence of ongoing selective myocardial necrosis in 88% of 50 individuals dying suddenly. Acute coronary thrombosis was rare. Since the morphological characteristics of the cell injury differ significantly from that seen in infarction and since the lesion may occur in individuals without significant epicardial coronary disease, factors other than permanent vascular obstruction are indicated as having a role in sudden cardiac death. Some other yet-unidentified process may alter susceptible myocardial cells.

摘要

通过形态学标准来区分心肌梗死和选择性累及心肌细胞的病变,作者在50例猝死个体中发现,88%存在持续性选择性心肌坏死的证据。急性冠状动脉血栓形成很少见。由于细胞损伤的形态学特征与梗死所见有显著差异,且该病变可能发生在无明显心外膜冠状动脉疾病的个体中,提示除永久性血管阻塞外的其他因素在心脏性猝死中起作用。一些其他尚未明确的过程可能会改变易损心肌细胞。

相似文献

1
Myocardial cell necrosis and sudden death in humans.人类心肌细胞坏死与猝死。
Circulation. 1975 Dec;52(6 Suppl):III60-2.
2
Pathology of atherosclerotic heart disease in sudden death. II. The significance of myocardial infarction.
Circulation. 1975 Dec;52(6 Suppl):III63-77.
3
Anatomoclinical correlations in coronary heart disease: recent advances and unanswered questions.冠心病的解剖临床相关性:最新进展与未解决的问题
Med Interne. 1989 Jan-Mar;27(1):3-14.
4
Anatomical pathology of sudden unexpected cardiac death.心性猝死的解剖病理学
Circulation. 1975 Dec;52(6 Suppl):III18-26.
5
[Histopathology of the myocardium in cases of sudden coronary death without myocardial infarct and postinfarct cardiosclerosis].[无心肌梗死及心肌梗死后心硬化的猝死病例中心肌的组织病理学]
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1988;11(2):50-4.
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[Histopathology and ultrastructure of focal myocardial injuries in sudden death from ischemic heart disease].[缺血性心脏病猝死中局灶性心肌损伤的组织病理学与超微结构]
Sud Med Ekspert. 1981 Jul-Aug;24(3):28-31.
7
[Changes in the myocardium of the atrium in sudden death due to ischemic heart disease].
Arkh Patol. 1975;37(4):30-7.
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[A case of sudden death from a muscle bridge spanning the anterior interventricular branch of the left coronary artery].[一例因横跨左冠状动脉前室间支的肌桥导致猝死的病例]
Arkh Patol. 1988;50(10):67-9.
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[Pathology of the myocardium and coronary vessels in sudden cardiac death. A post-mortem study of 130 cases].
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Sudden coronary death, fatal acute myocardial infarction and widespread coronary and myocardial inflammation.心脏性猝死、致命性急性心肌梗死以及广泛的冠状动脉和心肌炎症。
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