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[无心肌梗死及心肌梗死后心硬化的猝死病例中心肌的组织病理学]

[Histopathology of the myocardium in cases of sudden coronary death without myocardial infarct and postinfarct cardiosclerosis].

作者信息

Zhdanov V S, Galakhov I E, Veselova S P

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1988;11(2):50-4.

PMID:2466469
Abstract

231 cases of sudden coronary death of men aged 30-59 were studied; in 138 cases no focal cardiosclerosis of myocardium was observed; in 93 cases there were only few focuses less than 0.5 cm on diameter. In 83.2% of cases severe stenosis of coronary arteries (over 75%) was determined; it occurred more often in subjects aged 30-39 than in older persons. In all the cases myocardial lesions could be found out by dying the cuts with iron hematoxylin by the method of Rego and by investigation in polarized light. Contracture-altered segments of muscle fibers were often combined with hyper-relaxed segments, though in some cases one type alterations prevailed. Other cardiomyocyte alterations (vacuolization, hypertrophy, nucleus polymorphism, windings, fragmentation and so on) were more often in sudden coronary death than in the control group.

摘要

对231例年龄在30至59岁之间的男性冠状动脉猝死病例进行了研究;138例未观察到心肌局灶性硬化;93例仅有少数直径小于0.5厘米的病灶。在83.2%的病例中确定存在冠状动脉严重狭窄(超过75%);30至39岁的受试者比年长者更常出现这种情况。在所有病例中,通过用雷戈方法用苏木精铁对切片进行染色并在偏振光下进行检查,可以发现心肌病变。肌肉纤维的挛缩改变段常与过度松弛段合并,尽管在某些情况下一种类型的改变占主导。其他心肌细胞改变(空泡化、肥大、核多态性、缠绕、断裂等)在冠状动脉猝死中比在对照组中更常见。

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