Wu X, Cao J, Wu X, Han J, Li J
Department of Surgery, General Hospital of Nanjing Command, Chinese People's Liberotion Army, Nanjing 210002, China.
Zhonghua Wai Ke Za Zhi. 2000 Feb;38(2):98-100.
Transjugular intrahepatic portosystemic shunts (TIPS), a modified Sugiura procedure and TIPS plus a modified Sugiura procedure were compared to evaluate their clinical results in treatment of portal hypertension.
Ninety patients with portal hypertension respectively underwen TIPS (group I, n = 30), a modified Sugiura procedure (group II, n = 30) and TIPS plus a modified Sugiura procedure (group III, n = 30). The rates of rebleeding and encephalopathy, and the mortality of patients with portal hypertension were observed.
The early postoperative complications were observed in 23.33% of the patients in group I, in 30.0% of those in group II, and in 20.0% of those in group III. The early postoperative rates of rebleeding were 6.67% in group I, 10% in group II, and 0% in group III. Hepatic encephalopathy was seen in 16.67% of the patients in group I, 0% in group II and 13.33% in group III. The early mortality was 3.33% in group I. During follow-up for 1 - 36 months, the rates of rebleeding were 34.48% in group I, 33.33% in group II, and 3.33% in group III. The rates of encephalopathy and mortality were respectively 17.20% and 20.69% in group I, 3.33% and 13.33% in group II, 3.33% and 3.33% in group III. The shunt patency in group III was higher than that in group I.
Combination of TIPS and a modified Sugiura procedure can be effective to prevent and treat variceal bleeding.
比较经颈静脉肝内门体分流术(TIPS)、改良Sugiura手术以及TIPS联合改良Sugiura手术治疗门静脉高压症的临床效果。
90例门静脉高压症患者分别接受TIPS治疗(Ⅰ组,n = 30)、改良Sugiura手术(Ⅱ组,n = 30)以及TIPS联合改良Sugiura手术(Ⅲ组,n = 30)。观察门静脉高压症患者的再出血率、肝性脑病发生率及死亡率。
Ⅰ组患者术后早期并发症发生率为23.33%,Ⅱ组为30.0%,Ⅲ组为20.0%。Ⅰ组术后早期再出血率为6.67%,Ⅱ组为10%,Ⅲ组为0%。Ⅰ组患者肝性脑病发生率为16.67%,Ⅱ组为0%,Ⅲ组为13.33%。Ⅰ组早期死亡率为3.33%。随访1 - 36个月,Ⅰ组再出血率为34.48%,Ⅱ组为33.33%,Ⅲ组为3.33%。Ⅰ组肝性脑病发生率及死亡率分别为17.20%和20.69%,Ⅱ组分别为3.33%和13.33%,Ⅲ组分别为3.33%和3.33%。Ⅲ组分流道通畅率高于Ⅰ组。
TIPS联合改良Sugiura手术可有效防治静脉曲张出血。