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肝动脉栓塞术后肝内及肝外胆管损伤

[Damage to intra- and extrahepatic bile duct after hepatic artery embolization].

作者信息

Huang X, Huang Z, Duan W, Zhou N, Feng Y

机构信息

Department of Hepatobiliary Surgery, General Hospital, Chinese People's Liberation Army, Beijing 100853, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2000 Mar;38(3):169-72, 9.

Abstract

OBJECTIVE

To study the pathogenesis, treatment and prevention of bile duct damage arising from hepatic artery embolization.

METHODS

Five patients with intra- and extrahepatic biliary damage resulting from hepatic artery embolization. Of these patients, 4 were due to hepatic artery embolization for hepatic haemangioma, and 1 was due to injecting TH (methacrylate) compound into the hepatic artery during operation. The hepatic artery was injected with ethanol so as to evaluate liver damage in experimental rats.

RESULTS

All patients were found to have damage to intra- and extrahepatic bile duct at the hilum with biliary hepatocirrhosis; 4 of them received intrahepatic bile duct jejunal anastomosis and bile duct stent. Experiment result revealed obliteration of the bile duct and necrosis of the liver around the portal tract area.

CONCLUSIONS

Arterial embolization of hepatic haemangioma may cause severe biliary damage.

摘要

目的

研究肝动脉栓塞所致胆管损伤的发病机制、治疗及预防方法。

方法

5例因肝动脉栓塞导致肝内外胆管损伤的患者。其中,4例因肝动脉栓塞治疗肝血管瘤,1例因术中向肝动脉注入TH(甲基丙烯酸酯)化合物。向实验大鼠肝动脉注射乙醇以评估肝损伤。

结果

所有患者均发现肝门部肝内外胆管损伤并伴有胆汁性肝硬化;其中4例接受了肝内胆管空肠吻合术及胆管支架置入术。实验结果显示胆管闭塞及门管区周围肝组织坏死。

结论

肝血管瘤动脉栓塞可能导致严重的胆管损伤。

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