Kühner U, Blecher E A, Crétillat P, Gasser M, Pedrinis E, Tonella A
Dtsch Med Wochenschr. 1975 Oct 31;100(44):2246-51. doi: 10.1055/s-0028-1106530.
Observations on 29 children with Hodgkin's disease confirm that the initial spread, presence or absence of general symptoms, and histological type all have prognostic significance. The results of lymphangiography in 27, and laparotomy with multiple biopsies and splenectomy in 14 children demonstrated that - except in stage IV - both procedures are necessary for adequate classification as to stage of the disease. On the basis of these personal cases (5-year-survival rate of 53%) and published reports a therapeutic schema is suggested which is particularly appropriate for children.