[一种带有药物递送系统的新型扩张器的临床研究及化学药物对组织扩张的影响]

[Clinical study of a new expander with an agent delivery system and the effect of a chemical agent on tissue expansion].

作者信息

Liu W, Yang P, Man Z

机构信息

Beijing Huangsi Aesthetic Surgery Hospital, Beijing 100011, China.

出版信息

Zhonghua Zheng Xing Wai Ke Za Zhi. 2001 Nov;17(6):350-2.

PMID:11838059

Abstract

OBJECTIVE

To search for a method to enhance tissue expansion.

METHOD

A new type of expander with an agent delivery system was used to expand soft tissue in 15 patients. During expansion Papaverine was delivered through the delivery system into the tissue around the expanders.

RESULTS

It took 26 days to expand to the anticipated volume in the new expansion method group (NEM) and 51 days in the general expansion method group (GEM) (P < 0.01). Before operation the NEM group was over-expanded by 92.4% while the GEM group was over-expanded by 27.12%. At full expansion the blood flow of the expanded area of the two groups was 1.27 (NEM) and 0.64 (GEM). The immediate skin retraction of the two groups was 20.17% (NEM) and 38.26% (GEM).

CONCLUSION

The new expansion method can accelerate expansion speed and improve the quality of expanded skin and flap.

摘要

目的

探寻增强组织扩张的方法。

方法

采用一种带有药物输送系统的新型扩张器对15例患者进行软组织扩张。在扩张过程中，将罂粟碱通过输送系统注入扩张器周围组织。

结果

新扩张方法组（NEM）扩张至预期体积需26天，常规扩张方法组（GEM）需51天（P<0.01）。术前NEM组过度扩张92.4%，GEM组过度扩张27.12%。扩张充分时，两组扩张区域的血流量分别为1.27（NEM）和0.64（GEM）。两组即时皮肤回缩率分别为20.17%（NEM）和38.26%（GEM）。