Solano A, Oddone D, Croci F, Donateo P, Puggioni E, Brignole M
Centro Aritmologico, Ospedali Riuniti, Via Don Bobbio 16033 Lavagna, GE.
Ital Heart J Suppl. 2001 Dec;2(12):1303-7.
Patients suffering from heart failure are at high risk of arrhythmic death. Conventional pacemakers have not shown to affect mortality in patients with chronic heart failure and sick sinus syndrome, while this issue is established in patients with III degree or advanced atrioventricular block. Biventricular pacing has recently been introduced in clinical practice and the experience is limited; to date, only an improvement in symptoms and quality of life has been shown. Biventricular pacing with implantable cardioverter-defibrillator back-up is promising. The implantable cardioverter-defibrillator is able to reduce total and sudden mortality in high risk patients, as clearly demonstrated by several randomized clinical trials.
心力衰竭患者面临心律失常性死亡的高风险。传统起搏器尚未显示对慢性心力衰竭和病态窦房结综合征患者的死亡率有影响，而在三度或高度房室传导阻滞患者中这一问题已得到证实。双心室起搏最近已引入临床实践，经验有限；迄今为止，仅显示出症状和生活质量有所改善。带有植入式心脏复律除颤器备用装置的双心室起搏很有前景。植入式心脏复律除颤器能够降低高危患者的总死亡率和猝死率，这已被多项随机临床试验明确证实。
