新生儿磁心动图与傅里叶频谱分析。
Neonatal magnetocardiography and Fourier spectral analysis.
作者信息
Anninos P, Anastasiadis P G, Kotini A, Koutlaki N, Garas A, Galazios G
机构信息
Laboratory of Medical Physics, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
出版信息
Clin Exp Obstet Gynecol. 2001;28(4):249-52.
OBJECTIVE
In this study we investigated the relationship between heart rate variability (HRV) and respiration in healthy and probably asphyxiated infants using magnetocardiographic (MCG) recordings.
METHODS
Ten healthy and eight infants from pregnancies complicated by preeclampsia with indications of mild perinatal asphyxia were included in the study. All were near term. Maternal age ranged from 16 to 39 years (mean = 29.05, SD = 6.13). Spectral analysis was used to find out any association between respiration and HRV.
RESULTS
Respiratory sinus arrhythmia (RSA) was reduced in preeclamptic infants with indications of mild perinatal asphyxia. This difference was statistically significant (p < 0.0002, t-test), whereas the heart rate of the two groups was not statistically significant (p = 0.1, t-test).
CONCLUSION
The results suggest that infants with indications of mild preeclampsia differ from controls in respiratory activity and this difference is independent of basal heart rate. Thus, spectral analysis could be useful for the estimation of influence of mild perinatal asphyxia in the RSA rhythm of newborns.
目的
在本研究中，我们使用心磁图（MCG）记录来调查健康及可能存在窒息情况的婴儿的心率变异性（HRV）与呼吸之间的关系。
方法
本研究纳入了10名健康婴儿以及8名患有先兆子痫且有轻度围产期窒息迹象的婴儿。所有婴儿均接近足月。母亲年龄范围为16至39岁（平均 = 29.05，标准差 = 6.13）。采用频谱分析来找出呼吸与HRV之间的任何关联。
结果
有轻度围产期窒息迹象的先兆子痫婴儿的呼吸性窦性心律不齐（RSA）降低。这种差异具有统计学意义（p < 0.0002，t检验），而两组婴儿的心率无统计学意义（p = 0.1，t检验）。
结论
结果表明，有轻度先兆子痫迹象的婴儿在呼吸活动方面与对照组不同，且这种差异与基础心率无关。因此，频谱分析可能有助于评估轻度围产期窒息对新生儿RSA节律的影响。
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