Courville P, Favennec L, Viacroze C, Barrel A, Young P, Abboud P, Thomine E, Metayer J, Nouvet G
Service d'Anatomie Pathologique, CHRU Charles Nicolle Rouen, France.
J Cutan Pathol. 2002 Jan;29(1):55-8. doi: 10.1046/j.0303-6987.2001.00035.x.
Cryptococcosis and alternariosis are rare opportunistic infections often observed in immunocompromised patients. Because Cryptococcus and Alternaria are ubiquitous fungi found in soil, the presence of fungi in the dermis has to be observed on histological examination to confirm a real cutaneous, invasive, infection.
We report the first case of concomitant cutaneous cryptococcosis and cutaneous alternariosis, in an immunocompromised patient treated for a metastatic thymoma.
This observation underlines the fact that the possible co-existence of several rare infections in immunocompromised patients should take into consideration pathogen identification in order to adapt the therapy to individual patient requirements.
隐球菌病和链格孢菌病是罕见的机会性感染,常见于免疫功能低下的患者。由于隐球菌和链格孢菌是土壤中普遍存在的真菌,必须通过组织学检查观察真皮中真菌的存在,以确认真正的皮肤侵袭性感染。
我们报告了首例同时患有皮肤隐球菌病和皮肤链格孢菌病的病例,患者为一名接受转移性胸腺瘤治疗的免疫功能低下患者。
该病例强调了一个事实,即免疫功能低下患者可能同时存在多种罕见感染,应考虑病原体鉴定,以便根据个体患者的需求调整治疗方案。