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儿童使用丙胺卡因和罗哌卡因皮下输注麻醉的皮肤外科手术。

Dermatosurgery using subcutaneous infusion anesthesia with prilocaine and ropivacaine in children.

作者信息

Moehrle M, Breuninger H

机构信息

Department of Dermatology, University of Tuebingen, Tuebingen, Germany.

出版信息

Pediatr Dermatol. 2001 Nov-Dec;18(6):469-72. doi: 10.1046/j.1525-1470.2001.1862008.x.

Abstract

Pediatric surgical procedures under local anesthesia have been limited by the pain of injections and, because of low body weight, rapidly reached maximum doses. In subcutaneous infusion anesthesia (SIA) highly diluted local anesthetics are administered by flow- and volume-controlled infusion pumps. This article presents a retrospective review of the use of SIA in children undergoing excision of dermatologic problem lesions. A total of 354 surgical procedures, predominantly excisions of nevi in 271 children (3 months-16 years) were performed in 1999: 67 children were operated on under general anesthesia and 204 children with local anesthesia. For local anesthesia we used SIA with diluted prilocaine and ropivacaine (equivalent mixtures of 0.3%, 0.15%, 0.08%). The 67 children operated on under general anesthesia were younger (mean age 3.05 +/- 2.93 years, median age 2.00 years) than the 204 children who had surgery with SIA (mean age 9.00 +/- 4.2 years, median age 9.00 years). The sizes of excisions under general anesthesia were larger (maximum 1060 cm2, mean 76 +/- 225 cm2, median 7 cm2) than those under SIA (maximum 628 cm2, mean 22 +/- 100 cm2, median 3 cm2). No side effects of local anesthesia were observed in these pediatric procedures. The additional use of ropivacaine resulted in prolonged postoperative analgesia. SIA in children is a well-accepted, safe anesthesia that in some cases offers an alternative to general anesthesia.

摘要

局部麻醉下的小儿外科手术一直受到注射疼痛的限制,而且由于体重低,很快就会达到最大剂量。在皮下输注麻醉(SIA)中,高稀释度的局部麻醉药通过流量和容量控制的输注泵给药。本文对SIA在接受皮肤问题病变切除的儿童中的应用进行了回顾性研究。1999年共进行了354例外科手术,主要是对271名儿童(3个月至16岁)的痣进行切除:67名儿童接受全身麻醉手术,204名儿童接受局部麻醉手术。对于局部麻醉,我们使用了稀释的丙胺卡因和罗哌卡因进行SIA(0.3%、0.15%、0.08%的等效混合物)。接受全身麻醉手术的67名儿童(平均年龄3.05±2.93岁,中位年龄2.00岁)比接受SIA手术的204名儿童(平均年龄9.00±4.2岁,中位年龄9.00岁)年龄小。全身麻醉下切除的面积(最大1060平方厘米,平均76±225平方厘米,中位7平方厘米)比SIA下的面积(最大628平方厘米,平均22±100平方厘米,中位3平方厘米)大。在这些小儿手术中未观察到局部麻醉的副作用。额外使用罗哌卡因可延长术后镇痛时间。儿童SIA是一种广泛接受的安全麻醉方法,在某些情况下可替代全身麻醉。

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