An efficient route to alkyl chlorides from alcohols using the complex TCT/DMF.
作者信息
De Luca Lidia, Giacomelli Giampaolo, Porcheddu Andrea
机构信息
Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy.
出版信息
Org Lett. 2002 Feb 21;4(4):553-5. doi: 10.1021/ol017168p.
PMID:11843589
Abstract
[reaction: see text] Efficient conversion of alcohols and beta-amino alcohols to the corresponding chlorides (and bromides) can be carried out at room temperature in methylene chloride, using 2,4,6-trichloro[1,3,5]triazine and N,N-dimethyl formamide. This procedure can also be applied to optically active carbinols.
摘要
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