[Disseminated granuloma annulare].

A case of generalized granuloma annulare in a 55 year old man is reported. The disease appeared five years before the first admission to the hospital. A large number of bluish-red or skin-colour papules were scattered mainly around the earlobes, buttocks and on the extremities. Some of the lesions were lined up in rings or plaques. Small depigmented and brownish scars were present. Two biopsies revealed characteristic foci of complete collagen degeneration accompanied by a palisading infiltrate in the upper dermis. Treatment with tuberculostatics and antimalarics was without improvement. The lesions cleared after a course of prednison, but reappeared when the drug was discontinued.