Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
J Dermatol. 2011 May;38(5):482-5. doi: 10.1111/j.1346-8138.2010.01070.x. Epub 2010 Nov 2.
Granuloma annulare (GA) is characterized clinically as annularly-distributed, erythematous papules on the extremities in children and adolescents. GA is recognized histologically as palisading granulomas with central degenerated collagen and mucin deposits. Here, we present a case of concomitant occurrence of patch GA (PGA), the most rare type of GA, and classical GA in a patient. A 60-year-old man was referred to our hospital for asymptomatic eruptions on the upper arms, forearms, right flank and right lateral chest. Clinical examination revealed annular erythematous plaques composed of numerous small papules on bilateral upper arms and forearms. Moreover, an indurative, exudative erythematous to violaceous plaque was present on the right lateral chest and right flank. Histopathology of the former was compatible with palisade-type GA, and the latter interstitial-type GA. This is the first report of PGA concomitant with "classical" annular papular lesions.
环状肉芽肿（GA）的临床特征为儿童和青少年四肢呈环状分布的红斑性丘疹。GA 的组织学特征为栅栏状肉芽肿，伴有中央变性胶原和黏蛋白沉积。在此，我们报告了 1 例斑块状 GA（PGA）与经典 GA 同时发生的病例。1 名 60 岁男性因双侧上臂和前臂出现无症状性皮疹而被转诊至我院。临床检查显示双侧上臂和前臂有环状红斑性斑块，由许多小丘疹组成。此外，右侧侧胸和右侧侧胸有硬结性、渗出性红斑至紫蓝色斑块。前者的组织病理学检查符合栅栏型 GA，后者为间质性 GA。这是首例 PGA 伴“经典”环状丘疹病变的报告。
