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青春期前和青春期患者的睾丸内分泌功能与环磷酰胺

Testicular endocrine function and cyclophosphamide in prepubertal and pubertal patients.

作者信息

Andler W, Wahlen W, Kausch O, Krämer D, Rurainski W

出版信息

Helv Paediatr Acta. 1975 Oct;30(3):275-9.

PMID:1184397
Abstract

Testicular function was examined by means of HCG-stimulation tests in 6 prepubertal or pubertal patients with leukemia or malignant tumours during cytostatic therapy and in 5 patients with nephrotic syndrome after discontinuation of treatment. The results of urinary testosterone assays suggest no damaging effect of cyclophosphamide on Leydig cell function.

摘要

通过人绒毛膜促性腺激素刺激试验，对6例处于细胞抑制治疗阶段的青春期前或青春期白血病或恶性肿瘤患者以及5例停止治疗后的肾病综合征患者的睾丸功能进行了检查。尿睾酮检测结果表明，环磷酰胺对睾丸间质细胞功能无损害作用。

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