苯丁酸氮芥治疗期间的局灶性发作。
Focal fits during chlorambucil therapy.
作者信息
Naysmith A, Robson R H
出版信息
Postgrad Med J. 1979 Nov;55(649):806-7. doi: 10.1136/pgmj.55.649.806.
Abstract
An elderly man receiving chlorambucil for chronic lymphatic leukaemia developed focal fits. The onset and frequency were dose related. There was no evidence of metabolic disturbance or of meningeal leukaemia. Although reported in children and well recognized in animals, chlorambucil-induced fits in an adult have not been previously recorded.
摘要
一名正在接受苯丁酸氮芥治疗慢性淋巴细胞白血病的老年男性出现局灶性癫痫发作。发作的起始和频率与剂量相关。没有代谢紊乱或脑膜白血病的证据。虽然在儿童中已有报道且在动物中已得到充分认识，但苯丁酸氮芥诱发成人癫痫发作此前尚未有记录。
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