Giraud A L, Truy E, Frackowiak R
Physiology Department, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
Audiol Neurootol. 2001 Nov-Dec;6(6):381-93. doi: 10.1159/000046847.
Auditory re-afferentation by cochlear implants (CI) offers a unique opportunity to study directly from within the auditory modality plastic changes taking place at organisational levels up to the supra- or polymodal level. These plastic changes resulting from deafness and chronic electrical stimulation can be studied using modern neuroimaging techniques. In this paper, we review the available techniques and the experimental approaches to human studies of plasticity, we discuss the different forms of plasticity that are associated with cochlear implantation and we point to the interest of imaging studies for providing a prognosis of functional outcome after implantation.
人工耳蜗(CI)带来的听觉再传入为直接从听觉模式内部研究直至超模式或多模式水平的组织层面发生的可塑性变化提供了独特机会。可以使用现代神经成像技术研究由耳聋和慢性电刺激引起的这些可塑性变化。在本文中,我们回顾了现有的技术以及人类可塑性研究的实验方法,讨论了与人工耳蜗植入相关的不同形式的可塑性,并指出成像研究对于预测植入后功能结果的意义。