Hoperskaya O A
J Embryol Exp Morphol. 1975 Aug;34(1):253-64.
This paper describes the development of a mutant strain associated with periodic albinism (ap) in the clawed toad Xenopus laevis. The most outstanding feature of this mutation is the instability of the albino state. In the course of the development there is a succession of three periods of pigment expression: (1) complete absence of melanin pigment, (2) appearance of melanin in the pigmented epithelium of the eyes and in small quantities in skin melanophores, (3) disappearance of most pigment granules. Repeated spawnings show that the mutant syndrome is inherited as a recessive trait. Possible ways of analysing pigment cell differentiation with the use of the mutation described are discussed.
本文描述了非洲爪蟾（Xenopus laevis）中与周期性白化病（ap）相关的突变株的发育情况。该突变最显著的特征是白化状态的不稳定性。在发育过程中，有三个连续的色素表达阶段：（1）完全没有黑色素；（2）眼睛色素上皮中出现黑色素，皮肤黑素细胞中有少量黑色素；（3）大多数色素颗粒消失。多次产卵表明，突变综合征作为隐性性状遗传。文中讨论了利用所描述的突变分析色素细胞分化的可能方法。
