Bownes M
J Embryol Exp Morphol. 1975 Aug;34(1):33-54.
Drosophila embryos were damaged by microcautery at the cellular blastoderm stage at the sites of presumptive imaginal cells, identified from fate maps. The resulting adults were analyzed for abnormal structures. Cautery of any of the presumptive imaginal regions can lead to defects in the adult cuticle, though the majority of adults which hatch are morphologically normal. The abnormal adults had one or more discs either deleted, incompletely formed, or misarranged. Several of the structures which were incomplete had duplicated regions. The results suggest that, from the time fo their initial formation in the cellular blastoderm, a group of cells determined to be an 'adult' structure possesses a gradient of developmental capacity which is expressed by certain regions duplicating and other cells regenerating. The types of duplications found were similar to those resulting from other experimental treatments of imaginal discs at later stages in development, indicating that the presumptive imaginal disc cells, when they are first established in the cellular blastoderm, have a similar organization to mature imaginal discs.
果蝇胚胎在细胞胚盘阶段，于根据命运图谱确定的假定成虫盘细胞部位受到微烧灼损伤。对由此产生的成虫进行异常结构分析。烧灼任何一个假定成虫区域都可能导致成虫表皮出现缺陷，不过大多数孵化出的成虫在形态上是正常的。异常成虫有一个或多个成虫盘缺失、未完全形成或排列错乱。一些未完全形成的结构有重复区域。结果表明，从它们在细胞胚盘中最初形成之时起，一群注定会形成“成虫”结构的细胞具有发育能力梯度，这表现为某些区域重复以及其他细胞再生。所发现的重复类型与发育后期对成虫盘进行其他实验处理所产生的重复类型相似，这表明假定成虫盘细胞在细胞胚盘中首次形成时，其组织结构与成熟成虫盘相似。
