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计划性新生儿起搏器植入术后的自体胎盘输血

Autologous placental blood transfusion after a planned neonatal pacemaker implantation.

作者信息

Domanović D, Zavrsnik T, Vesel S

机构信息

Blood Transfusion Centre of Slovenia, Slajmerjeva 6, 1000 Ljubljana, Slovenia.

出版信息

Transfus Med. 2001 Dec;11(6):459-61. doi: 10.1046/j.1365-3148.2001.00333.x.

Abstract

A fetal third-degree atrio-ventricular block was diagnosed in a 22-year-old woman at 24 weeks of gestation. During clinical follow-up a mild to moderate tricuspid regurgitation was detected at 35 weeks and maternal connective tissue diseases were excluded. Early postnatal cardiac pacing therapy was planned and autologous placental blood transfusion was proposed for the treatment of probable blood loss due to pacemaker implantation. A male infant was delivered at 38 weeks vaginally and 87 mL of placental blood was collected from the undelivered placenta. The placental blood was negative for viral markers and syphilis. Subsequent tests for bacteriological cultures were also negative. Within 6 h of delivery, the baby underwent cardiac pacemaker implantation and received 45 mL of autologous placental blood. Autologous placental blood transfusion was successfully used for the treatment of predicted blood loss after a planned neonatal surgical procedure.

摘要

一名22岁女性在妊娠24周时被诊断出胎儿三度房室传导阻滞。临床随访期间,在35周时检测到轻度至中度三尖瓣反流,排除了母体结缔组织疾病。计划在产后早期进行心脏起搏治疗,并提议进行自体胎盘输血,以治疗因起搏器植入可能导致的失血。一名男婴于38周经阴道分娩,从未娩出的胎盘中采集了87毫升胎盘血。胎盘血的病毒标志物和梅毒检测均为阴性。随后的细菌培养检测也为阴性。婴儿在出生后6小时内接受了心脏起搏器植入,并输注了45毫升自体胎盘血。自体胎盘输血成功用于治疗计划中的新生儿外科手术后预计的失血。

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