Nelson M F, Melton R E, Wazer J R
J Nucl Med. 1975 Nov;16(11):1043-8.
When used is conjunction with stannous ion and 99Tc, the nonsequestering, cyclic, trimeric phosphate anion, (P309)3-, introduced in the form of its sodium salt, exhibits admirable properties as a bone-visualizing agent as demonstrated by animal studies. These studies show that this combinatation is easily prepared reproducibly and, compared to the agents described in the recent literature (all based on sequestering phosphates), is at least equivalent for bone visualization while being considerably less toxic.
当与亚锡离子和99Tc结合使用时，以钠盐形式引入的非螯合性、环状、三聚磷酸根阴离子(P309)3-，作为一种骨显像剂表现出令人钦佩的特性，动物研究已证实这一点。这些研究表明，这种组合易于重复制备，并且与最近文献中描述的显像剂（均基于螯合磷酸盐）相比，在骨显像方面至少相当，而毒性要小得多。
