Nosik M N, Matsevich G R
Vopr Virusol. 2002 Jan-Feb;47(1):4-8.
Data on cellular receptors playing an important role in penetration of HIV into the cell and determining further development of HIV infection are reviewed. Special attention is paid to chemokine receptors CCR5 and CXCR4. The resistance of some humans to HIV-1 infection, probably due to defective CCR5 gene allele, is discussed.
本文综述了细胞受体在HIV侵入细胞及决定HIV感染后续发展过程中发挥重要作用的数据。特别关注趋化因子受体CCR5和CXCR4。讨论了一些人对HIV-1感染具有抗性的原因,这可能是由于CCR5基因等位基因缺陷所致。