Choi Changsun, Ham Hee-Jin, Kwon Donghyok, Kim Junghyun, Cheon Doo-Sung, Min Kyoungsub, Cho Wan-Seob, Chung Han-Kook, Jung Taewon, Jung Kwonil, Chae Chanhee
Department of Veterinary Pathology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Kyounggi-Do, Republic of Korea.
J Vet Med Sci. 2002 Jan;64(1):71-3. doi: 10.1292/jvms.64.71.
The in vitro susceptibilities of 285 isolates of Escherichia coli from preweaned and postweaned pigs with diarrhea and edema disease were tested with the 15 commonly used antimicrobial drugs by an agar dilution minimal inhibitory concentration procedure according to National Committee for Clinical Laboratory Standards (NCCLS) guidelines. All E. coli isolates tested in this study belonged to enterotoxigenic E. coli, attaching and effacing E. coli, or Shiga toxin-producing E. coli. Field isolates had low MIC90 for ceftiofur (1 microg/ml). No correlation in antimicrobial resistance was found in three types of E. coli.
按照美国国家临床实验室标准委员会（NCCLS）的指南，采用琼脂稀释法测定最低抑菌浓度，用15种常用抗菌药物对285株来自断奶前和断奶后腹泻及水肿病猪的大肠杆菌进行体外药敏试验。本研究中检测的所有大肠杆菌分离株均属于产肠毒素大肠杆菌、黏附性大肠杆菌或产志贺毒素大肠杆菌。田间分离株对头孢噻呋的MIC90较低（1微克/毫升）。在三种类型的大肠杆菌中未发现耐药性的相关性。
