Wang L, Zhang Y, Wang Y, Wang G, Lu J, Deng J
Henan Institute of Ophthalmology, Zhengzhou 450003, China.
Zhonghua Yan Ke Za Zhi. 2000 Mar;36(2):138-40.
To investigate the spectrum of mycotic keratitis in China.
We scraped and evaluated 615 mycotic keratitis in microbiology laboratories of Zhengzhou (central China), Shijiazhuang (north China) and Guangzhou (south China) in the twenty-two years between Jan. 1, 1975 and Jun. 30, 1997.
Organisms of 18 genuses and 615 species isolated from corneal ulcers were found. Fusarium species were isolated the most frequently (65.0% in Zhengzhou, 33.3% in Shijiazhuang and 39.2% in Guangzhou), followed by Aspergillus (20.5% in Zhengzhou, 21.7% in Shijiazhuang, 30.7% in Guangzhou), Penicillium (3.6% in Zhengzhou, 11.6% in Shijiazhuang) and Curvularis (13.1% in Guangzhou). Between Jan. 1, 1975 and Dec. 31, 1986, Aspergillus species were most commonly isolated in Guangzhou (48.5%), followed by Fusarium (27.7%) and Penicillium (14.27%).
Just as different regions of the world are characterized by specific endemic infections, the predominating organisms in corneal fungal infections also vary throughout the world. These regional differences in causative organisms in mycotic keratitis are clinically important because they influence the initial and more definite therapy. This study shows that Fusarium species are the most common organisms of mycotic keratitis in China.
调查中国真菌性角膜炎的菌种谱。
在1975年1月1日至1997年6月30日的22年间，我们在郑州（中国中部）、石家庄（中国北部）和广州（中国南部）的微生物实验室刮取并评估了615例真菌性角膜炎病例。
从角膜溃疡中分离出18个属615种微生物。镰刀菌属分离率最高（郑州为65.0%，石家庄为33.3%，广州为39.2%），其次是曲霉菌属（郑州为20.5%，石家庄为21.7%，广州为30.7%）、青霉菌属（郑州为3.6%，石家庄为11.6%）和弯孢霉菌属（广州为13.1%）。1975年1月1日至1986年12月31日期间，广州分离出的曲霉菌属最为常见（48.5%），其次是镰刀菌属（27.7%）和青霉菌属（14.27%）。
正如世界不同地区有特定的地方性感染一样，角膜真菌感染中的主要病原体在世界各地也有所不同。真菌性角膜炎病原体的这些地区差异在临床上很重要，因为它们会影响初始治疗和更确切的治疗。本研究表明，镰刀菌属是中国真菌性角膜炎最常见的病原体。
