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非裔美国女性和白人女性对更年期的认知及其对参与激素替代疗法临床试验意愿的影响。

The perceptions of menopause of African-American and white women and affect on willingness to participate in a HRT clinical trial.

作者信息

Strickland O L, Dunbar S B

机构信息

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta VA Medical Center, Atlanta, GA, USA.

出版信息

J Natl Black Nurses Assoc. 2000 Jan;11(1):43-50.

Abstract

Menopause is a normal developmental process for women; however, few studies of healthy menopausal women and African-American women have been reported. While hormone replacement therapy (HRT) has been touted as a treatment for menopausal women, clinical trials of HRT still need to be conducted to determine its potential positive and negative effects. This is a focus group study of 21 women of menopausal age (11 African-Americans and 10 White women) to determine their experiences with menopause and their willingness to participate in a HRT clinical trial. Results indicated generally positive attitudes toward menopause and a variety of symptoms of varying degrees of severity in African-American and White women. Limited knowledge about menopause and HRT were apparent; however, White women were more likely to be receiving HRT and were more informed about HRT than African-American women. White women also were more positive about participating in a HRT clinical trial than African-American women who feared cancer as a potential side effect.

摘要

绝经是女性正常的发育过程;然而,关于健康绝经女性和非裔美国女性的研究报道较少。虽然激素替代疗法(HRT)一直被吹捧为绝经女性的一种治疗方法,但仍需进行HRT临床试验以确定其潜在的正负效应。这是一项针对21名绝经年龄女性(11名非裔美国女性和10名白人女性)的焦点小组研究,旨在确定她们的绝经经历以及参与HRT临床试验的意愿。结果表明,非裔美国女性和白人女性对绝经总体持积极态度,且存在各种不同严重程度的症状。关于绝经和HRT的知识明显有限;然而,白人女性比非裔美国女性更有可能接受HRT,并且对HRT了解更多。与担心癌症作为潜在副作用的非裔美国女性相比,白人女性对参与HRT临床试验也更积极。

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