Winter William E, Seidman Jeffery, Krivak Thomas C, Pujari Susan G, Boice Charles R, Carlson Jay W
Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, DC 20307, USA.
Gynecol Oncol. 2002 Mar;84(3):453-5. doi: 10.1006/gyno.2001.6505.
Epithelial carcinomas of the ovary are predominantly an intraperitoneal disease. Reports of epithelial ovarian carcinomas metastatic to the pericardium are rare.
A 43-year-old woman was admitted with symptoms of a pericardial tamponade, as well as an embolic cerebrovascular accident, and transferred to the ICU where a pericardiocentesis was performed. Cytology revealed malignant cells in the pericardial fluid. CT scan of the abdomen and pelvis revealed bilateral pelvic masses. A laparotomy revealed a papillary serous adenocarcinoma of ovarian primary and an infarcted spleen with capsular tumor metastases. The malignant cells in the pericardial fluid were consistent with the ovarian primary.
Ovarian cancer metastasis to the heart and pericardium presented an aggressive variant of tumor spread with significant morbidity and subsequent mortality.
卵巢上皮癌主要是一种腹膜内疾病。卵巢上皮癌转移至心包的报道很少见。
一名43岁女性因心包填塞症状以及栓塞性脑血管意外入院，并被转入重症监护病房，在那里进行了心包穿刺术。细胞学检查显示心包积液中有恶性细胞。腹部和盆腔CT扫描显示双侧盆腔肿块。剖腹手术显示为卵巢原发性乳头状浆液性腺癌以及脾脏梗死伴包膜肿瘤转移。心包积液中的恶性细胞与卵巢原发性肿瘤一致。
卵巢癌转移至心脏和心包是一种侵袭性的肿瘤扩散形式，具有显著的发病率和随后的死亡率。
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