University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
Arch Gynecol Obstet. 2009 Oct;280(4):675-8. doi: 10.1007/s00404-009-0976-5. Epub 2009 Feb 19.
Malignant pericardial effusion with cardiac tamponade is an uncommon metastatic manifestation of gynecologic cancers. We describe a patient with ovarian cancer who developed pericardial effusion with cardiac tamponade and was successfully treated with pericardiocentesis and intrapericardial instillation of thiotepa.
A 52-year-old woman with stage IV ovarian adenocarcinoma presented with worsening cough, dyspnea, and fatigue. Chest X-ray and echocardiogram confirmed the presence of pericardial effusion with cardiac tamponade. Pericardial fluid cytology revealed adenocarcinoma. Treatment consisted of pericardiocentesis with thiotepa sclerotherapy. She survived 12 months post-therapy without recurrent pericardial tamponade.
Patients with gynecologic cancers may develop a pericardial effusion with cardiac tamponade. Malignant pericardial effusion should be included in the differential diagnosis in patients with recurrent ovarian cancer who present with cardiac tamponade.
恶性心包积液伴心脏压塞是妇科癌症少见的转移性表现。我们描述了一位卵巢癌患者，她发生心包积液伴心脏压塞，并成功地接受了心包穿刺和噻替派心包内灌注治疗。
一位 52 岁女性患有 IV 期卵巢腺癌，表现为咳嗽加重、呼吸困难和乏力。胸部 X 线和超声心动图证实存在心包积液伴心脏压塞。心包积液细胞学检查显示为腺癌。治疗包括心包穿刺和噻替派硬化治疗。患者在治疗后 12 个月存活，无复发性心包压塞。
妇科癌症患者可能发生心包积液伴心脏压塞。对于出现心脏压塞的复发性卵巢癌患者，应将恶性心包积液纳入鉴别诊断。
