Grocott M P W, Hamilton M A
Centre for Anaesthesia, University College London, London, UK.
Vox Sang. 2002 Jan;82(1):1-8. doi: 10.1046/j.1423-0410.2002.00123.x.
The aim of this review was to summarize the properties of the commonly available resuscitation fluids and highlight where knowledge of the characteristics of individual fluids might guide their use in clinical practice. Some of the current controversies surrounding resuscitation fluids are also discussed. Blood or blood products, or strategies of fluid administration, are not focused upon.
The clinical trial data does not support the concept of a therapeutic advantage for either crystalloids or colloids, despite claimed theoretical advantages for both classes of fluid. The available colloid solutions have quite distinct profiles of activity, both in terms of their plasma volume expansion profile and other physiological and pharmacological properties. Recent data suggests that physiologically balanced crystalloid and colloid solutions may improve clinical outcomes when compared with saline-based fluids.
本综述旨在总结常用复苏液体的特性，并强调了解每种液体的特性在临床实践中对指导其使用的作用。还讨论了当前围绕复苏液体的一些争议。本综述未聚焦于血液或血液制品，也未涉及液体输注策略。
尽管晶体液和胶体液在理论上均有各自的优势，但临床试验数据并不支持其中某一类液体具有治疗优势的观点。现有的胶体溶液在血浆容量扩充方面以及其他生理和药理特性方面，具有截然不同的活性特征。最近的数据表明，与以生理盐水为基础的液体相比，生理平衡的晶体液和胶体液可能会改善临床结局。
