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动物模型中骨骺骨折的早期与晚期复位

Early versus late reduction of a physeal fracture in an animal model.

作者信息

Egol Kenneth A, Karunakar Madhav, Phieffer Laura, Meyer Ralph, Wattenbarger J Michael

机构信息

Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA.

出版信息

J Pediatr Orthop. 2002 Mar-Apr;22(2):208-11.

PMID:11856932
Abstract

This study was designed to determine whether delayed reduction of physeal fractures in an animal model causes growth disturbance, and whether final alignment is better in delayed or malreduced fractures. Salter 1 fractures of the proximal tibia were created in 41 immature rats randomized into five groups. The fractures were reduced as follows: group 1, immediately; group 2, 6 hours; group 3, 24 hours; group 4, 48 hours; and group 5, left malreduced. Both legs were analyzed for leg-length discrepancy, angular deformity, and evidence of radiographic bar. No radiographic physeal bar or leg-length discrepancy was seen among any of the groups. Angular deformity was greatest in group 5 and least in group 1. Immediate reduction resulted in the least angular deformity. Delayed reduction showed no evidence of physeal damage, physeal growth disturbance, or radiographic bar formation. Alignment was not improved in delayed reduction versus malreduced fractures.

摘要

本研究旨在确定在动物模型中,骨骺骨折延迟复位是否会导致生长障碍,以及延迟或复位不良的骨折最终对线情况是否更好。将41只未成熟大鼠随机分为五组,造成近端胫骨的Salter 1型骨折。骨折复位情况如下:第1组立即复位;第2组6小时后复位;第3组24小时后复位;第4组48小时后复位;第5组保持复位不良。对双腿进行腿长差异、角畸形和影像学骨桥证据分析。所有组均未发现影像学骨骺骨桥或腿长差异。第5组角畸形最大,第1组最小。立即复位导致的角畸形最小。延迟复位未显示骨骺损伤、骨骺生长障碍或影像学骨桥形成的证据。与复位不良的骨折相比,延迟复位对线情况并未改善。

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