McElrath Thomas F, Norwitz Errol R, Nour Nawal, Robinson Julian N
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Am J Perinatol. 2002 Jan;19(1):9-15. doi: 10.1055/s-2002-20176.
The objective of this study is to investigate the current understanding of neonatal survival and the willingness to provide aggressive obstetric intervention at the limit of fetal viability among practicing perinatologists in the United States. A pretested survey was mailed to members of the Society for Maternal Fetal Medicine. The survey identified the practitioner's opinion of the lowest limit of viability and gestational ages at which antenatal steroids and cesarean section would first be provided. We also attempted to identify practitioner knowledge of survival at 23 and 24 weeks' gestation and years of perinatal practice. Of the 1244 surveys mailed to members of the Society for Maternal-Fetal Medicine practicing in the United States, 462 practitioners replied for a 37% response rate. Fifty percent considered the lower limit of viability to be 24 weeks' and 44.3% believed the lower limit of viability to be 23 weeks' gestation. Among respondents, the majority estimated a 0 to 10% survival rate at 23 weeks' and 25 to 50% survival rate at 24 weeks. Only 13% of respondents correctly estimates survival at 23 weeks' gestation as >25%, and only 17% correctly estimated survival at 24 weeks' at >50%. Among practitioners, 43.6% would first give antenatal steroids after 24 weeks' gestation but 55.6%would administer steroids before the beginning of week 24. Twenty-eight percent would routinely monitor a fetus less than 24 weeks' gestation. Consistent with this observation, 21% would perform a cesarean section before 24 weeks' gestation. We find that respondents underestimate the consensus in the most recent literature on survival of infants born at 23 to 24 weeks. This underestimation may lead to a limitation in interventions offered.
本研究的目的是调查美国围产医学从业者目前对新生儿存活的理解以及在胎儿存活极限时提供积极产科干预的意愿。一份经过预测试的调查问卷被邮寄给母胎医学协会的成员。该调查确定了从业者对于可存活最低孕周以及首次给予产前类固醇激素和剖宫产的孕周的看法。我们还试图确定从业者关于孕23周和24周时的存活情况的知识以及围产期从业年限。在邮寄给在美国执业的母胎医学协会成员的1244份调查问卷中,462名从业者回复,回复率为37%。50%的人认为可存活下限为24周,44.3%的人认为可存活下限为孕23周。在受访者中,大多数人估计孕23周时的存活率为0%至10%,孕24周时的存活率为25%至50%。只有13%的受访者正确估计孕23周时的存活率大于25%,只有17%的人正确估计孕24周时的存活率大于50%。在从业者中,43.6%的人会在孕24周后首次给予产前类固醇激素,但55.6%的人会在孕24周开始前给予类固醇激素。28%的人会常规监测孕周小于24周的胎儿。与此观察结果一致的是,21%的人会在孕24周前进行剖宫产。我们发现,受访者低估了关于23至24周出生婴儿存活情况的最新文献中的共识。这种低估可能会导致所提供干预措施的局限性。