Rapp C, Debord T, Imbert P, Lambotte O, Roué R
Service des maladies infectieuses et tropicales, hôpital d'instruction des armées Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France.
Rev Med Interne. 2002 Jan;23(1):85-91. doi: 10.1016/s0248-8663(01)00518-5.
Spontaneous splenic ruptures are rare but life-threatening complications of infectious diseases. Splenectomy is still the treatment of choice but numerous recent reports have documented favorable outcome with conservative treatment.
We report three cases of splenic rupture occurring respectively with infectious mononucleosis, P. vivax infection and dengue fever. Diagnosis, treatment and indications are reviewed, an approach to management is suggested. The study included three military men respectively aged 23, 24 and 35 years, admitted for acute abdominal pain in the left upper quadrant. The abdominal computed tomography confirmed partial rupture (splenic hematoma) in the first two cases, and an hemoperitoneum in the dengue case. Splenic ruptures can reveal or complicate an evolving infection. Rupture can happen spontaneously or as a result of trauma, which may be minor and unnoticed. The typical presentation is acute, but progressive forms are described. The diagnosis is made by ultrasound and CT scan. Splenectomy dogma tends to be supplanted by conservative treatment. Non-operative management can be successful if appropriate criteria and a long period of follow-up are applied in carefully selected cases. When an operative approach is selected, conservative surgical treatment is attractive. Splenectomy should be reserved for patients with uncontrollable rupture or with recurrent splenic bleeding.
Spontaneous splenic rupture are uncommon in infectious diseases. A multidisciplinary management is necessary. A conservative treatment should be considered in selected, closely monitored patients.
自发性脾破裂是传染病中罕见但危及生命的并发症。脾切除术仍是首选治疗方法,但最近有许多报告记录了保守治疗的良好效果。
我们报告了三例分别由传染性单核细胞增多症、间日疟原虫感染和登革热引起的脾破裂病例。对诊断、治疗和适应症进行了综述,并提出了一种管理方法。该研究包括三名军人,年龄分别为23岁、24岁和35岁,因左上腹急性腹痛入院。腹部计算机断层扫描证实前两例为部分破裂(脾血肿),登革热病例为腹腔积血。脾破裂可能揭示或并发正在发展的感染。破裂可自发发生或由外伤引起,外伤可能轻微且未被注意到。典型表现为急性,但也有渐进性形式的描述。诊断通过超声和CT扫描进行。脾切除的教条正逐渐被保守治疗所取代。如果在精心挑选的病例中应用适当的标准并进行长期随访,非手术治疗可能会成功。当选择手术方法时,保守性手术治疗具有吸引力。脾切除术应仅用于破裂无法控制或反复脾出血的患者。
传染病中自发性脾破裂并不常见。多学科管理是必要的。对于经过挑选且密切监测的患者,应考虑保守治疗。