Khokhar D Sudarshan, Sethi Harinder Singh, Kumar Harsh, Sudan Rajeev, Sharma Namrata, Nayak Niranjan
Cornea Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.
Cornea. 2002 Mar;21(2):232-3. doi: 10.1097/00003226-200203000-00024.
To describe a postkeratoplasty endophthalmitis owing to Alcaligenes faecalis that resolved with medical management.
Case report and review of literature.
To best of our knowledge, postkeratoplasty endophthalmitis caused by A. faecalis has not been reported in literature. The source of infection was found to be the donor tissue. The organism isolated was resistant to gentamicin, which was the only antibiotic present in the storage medium (McCarey and Kaufman medium). The patient was treated aggressively with topical, systemic and intravitreal antibiotics. The endophthalmitis resolved completely within two weeks.
A. faecalis is a gram negative, non-spore forming rod that can cause endophthalmitis if donor tissue is contaminated with the organism. Clinical suspicion, review of bacterial culture and sensitivity report from donor tissue, anterior chamber and vitreous taps, along with early therapy with appropriate antibiotics can lead to resolution of infection.
描述一例因粪产碱杆菌引起的角膜移植术后眼内炎，经药物治疗后痊愈。
病例报告及文献复习。
据我们所知，文献中尚未报道过由粪产碱杆菌引起的角膜移植术后眼内炎。感染源为供体组织。分离出的病原体对庆大霉素耐药，而庆大霉素是储存培养基（麦凯里和考夫曼培养基）中唯一存在的抗生素。患者接受了局部、全身及玻璃体腔内抗生素的积极治疗。眼内炎在两周内完全消退。
粪产碱杆菌是一种革兰氏阴性、无芽孢形成的杆菌，如果供体组织被该病原体污染，可导致眼内炎。临床怀疑、对供体组织、前房和玻璃体穿刺液的细菌培养及药敏报告进行复查，以及早期使用适当抗生素进行治疗，可使感染得到消退。
