Paulson D L
J Thorac Cardiovasc Surg. 1975 Dec;70(6):1095-104.
Carcinomas in the superior pulmonary sulcus produce a clinical pattern peculiar to their location. Pancoast (1932) defined tumors in this precise location and described a characteristic group of clinical findings now known as the Pancoast syndrome. Experience with a total of 92 patients with primary carcinomas in the superior pulmonary sulcus treated by combined preoperative irradiation and extended resection in 61 patients (66 per cent) reveals 16 of 46 patients eligible surviving over 5 years (34 per cent) and eight of 30 patients alive over 10 years (29 per cent). Stage of nodal involvement, extent of the tumor, cell type, and pathological effects of preoperative irradiation in the resected specimens are the important factors in prognosis.
肺上沟癌因其所在位置而产生一种独特的临床症状。潘科斯特(1932年)明确了这一精确位置的肿瘤,并描述了一组现在被称为潘科斯特综合征的典型临床发现。对61例(66%)接受术前联合放疗及扩大切除术治疗的92例原发性肺上沟癌患者的经验显示,46例符合条件的患者中有16例存活超过5年(34%),30例存活患者中有8例存活超过10年(29%)。淋巴结受累分期、肿瘤范围、细胞类型以及切除标本中术前放疗的病理效应是影响预后的重要因素。