Nikolaos Panagopoulos, Vasilios Livaditis, Efstratios Koletsis, Panagiotis Alexopoulos, Christos Prokakis, Nikolaos Baltayiannis, Antonios Hatzimichalis, Tsakiridis Kosmas, Zarogoulidis Paul, Zarogoulidis Konstantinos, Katsikogiannis Nikolaos, Kougioumtzi Ioanna, Machairiotis Nikolaos, Tsiouda Theodora, Machairiotis Nikolaos, Madesis Athanasios, Vretzakis Georgios, Kolettas Alexandros, Dimitrios Dougenis
1 Department of Cardiothoracic Surgery, Patras University School of Medicine, Patra, Greece ; 2 Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece ; 3 Cardiothoracic Surgery Department, "Saint Luke" Private Clinic of Health Excellence, Thessaloniki, Panorama, Greece ; 4 Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 5 Surgery Department (NHS), University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 6 Internal Medicine Department, "Theagenio" Cancer Hospital, Thessaloniki, Greece ; 7 Cardiothoracic Surgery Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 8 Anesthesiology Department, University of Larisa, Larisa, Greece ; 9 Anesthesiology Department, "Saint Luke" Private Clinic of Health Excellence, Thessaloniki, Panorama, Greece.
J Thorac Dis. 2014 Mar;6 Suppl 1(Suppl 1):S180-93. doi: 10.3978/j.issn.2072-1439.2013.12.31.
A Pancoast tumor, also called a pulmonary sulcus tumor or superior sulcus tumor, is a tumor of the pulmonary apex. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung. It typically spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non-small cell cancers. The growing tumor can cause compression of a brachiocephalic vein, subclavian artery, phrenic nerve, recurrent laryngeal nerve, vagus nerve, or, characteristically, compression of a sympathetic ganglion resulting in a range of symptoms known as Horner's syndrome. Pancoast tumors are named for Henry Pancoast, a US radiologist, who described them in 1924 and 1932.The treatment of a Pancoast lung cancer may differ from that of other types of non-small cell lung cancer (NSCLC). Its position and close proximity to vital structures may make surgery difficult. As a result, and depending on the stage of the cancer, treatment may involve radiation and chemotherapy given prior to surgery. Surgery may consist of the removal of the upper lobe of a lung together with its associated structures as well as mediastinal lymphadenectomy. Surgical access may be via thoracotomy from the back or the front of the chest and modification. Careful patient selection, improvements in imaging such as the role of PET-CT in restaging of tumors, radiotherapy and surgical advances, the management of previously inoperable lesions by a combined experienced thoracic-neurosurgical team and prompt recognition and therapy of postoperative complications has greatly increased local control and overall survival for patients with these tumors.
潘科斯特瘤，也称为肺沟瘤或肺尖沟瘤，是一种肺尖部肿瘤。它是一种肺癌，主要根据其位于右肺或左肺顶端的位置来定义。它通常会扩散到附近组织，如肋骨和椎骨。大多数潘科斯特瘤是非小细胞癌。不断生长的肿瘤会压迫头臂静脉、锁骨下动脉、膈神经、喉返神经、迷走神经，或者典型地，压迫交感神经节，导致一系列称为霍纳综合征的症状。潘科斯特瘤以美国放射科医生亨利·潘科斯特命名，他在1924年和1932年对其进行了描述。潘科斯特肺癌的治疗可能与其他类型的非小细胞肺癌（NSCLC）不同。其位置以及与重要结构的紧密相邻可能使手术困难。因此，根据癌症的阶段，治疗可能包括在手术前进行放疗和化疗。手术可能包括切除肺的上叶及其相关结构以及纵隔淋巴结清扫术。手术入路可以通过胸部后方或前方的开胸手术并进行改良。仔细的患者选择、成像技术的改进，如PET-CT在肿瘤再分期中的作用、放疗和手术进展、由经验丰富的胸科-神经外科联合团队对以前无法手术的病变进行管理以及对术后并发症的及时识别和治疗，极大地提高了这些肿瘤患者的局部控制率和总生存率。
