Donike M
Br J Sports Med. 1976 Oct;10(3):147-54. doi: 10.1136/bjsm.10.3.147-a.
Gas chromatographic screening procedures have been evaluated which permit the detection of stimulants and sedatives in blood after administration of pharmacological doses. The techniques actually used in sample preparations and gas chromatographic work are presented as well as examples of pharmacokinetic studies and postive dope cases. The use of sensitive and selective detectors like the nigrogen-specific detector or a mass spectrometer is absolutely essential for routine work, as for non-specific detectors the number of "false positives" leads to an intolerable work load for the laboratory.
已对气相色谱筛选程序进行了评估，这些程序可在给予药理剂量后检测血液中的兴奋剂和镇静剂。文中介绍了样品制备和气相色谱工作中实际使用的技术，以及药代动力学研究和阳性兴奋剂案例的示例。对于常规工作而言，使用像氮特异性检测器或质谱仪这样灵敏且选择性高的检测器绝对至关重要，因为对于非特异性检测器，“假阳性”的数量会给实验室带来难以承受的工作量。
