Piana S, Gelli M C, Cavazza A, Serra L, Gardini G
Servizio di Anatomia ed Istologia Patologica, Ospedale Santa Maria Nuova, Reggio Emilia, Italy.
Pathol Res Pract. 2002;198(1):51-4. doi: 10.1078/0344-0338-00184.
We report a case of an intranodal schwannoma in a 79-year-old woman. The patient underwent a left colectomy for a colonic adenocarcinoma, with regional lymph node dissection. Macroscopic examination of the specimen revealed a well-circumscribed 4 cm nodule located in the pericolic fat. Macroscopically, it was interpreted as a metastatic lymph node. Microscopically, the nodule was composed of a proliferation of bland spindle cells, was immunohistochemically positive for S100 protein, and negative for smooth muscle actin, desmin, and cytokeratin. The pathological findings led to the diagnosis of a very rare case of primary schwannoma of the lymph node.
我们报告一例79岁女性的淋巴结内神经鞘瘤。该患者因结肠腺癌接受了左半结肠切除术及区域淋巴结清扫术。对标本进行宏观检查发现，在结肠旁脂肪中有一个边界清晰的4厘米结节。肉眼观察，其被认为是一个转移性淋巴结。显微镜下，该结节由大量温和的梭形细胞增殖构成，免疫组化结果显示S100蛋白呈阳性，而平滑肌肌动蛋白、结蛋白和细胞角蛋白呈阴性。病理结果诊断为一例非常罕见的原发性淋巴结神经鞘瘤。
