Nguyen Ha T, Black Sandra A, Ray Laura A, Espino David V, Markides Kyriakos S
Center on Aging, University of Texas Medical Branch, Galveston 77555-1153, USA.
J Gerontol A Biol Sci Med Sci. 2002 Mar;57(3):M181-5. doi: 10.1093/gerona/57.3.m181.
The purpose of this analysis was to examine the association of sociodemographic variables and health-related conditions with 5-year declines in cognitive function among Mexican American elderly persons.
The cognitive function of 1759 participants was assessed by using the Mini-Mental State Examination (MMSE) in 1993/1994 and again in 1998/1999. Cognitive decline was defined by two sets of criteria: (1) a drop to 17 or below on the MMSE at follow-up, and (2) a decline of at least three points, the mean change in MMSE scores among respondents who obtained scores at or above the 5th percentile distribution at baseline.
Cognitive decline was significantly associated with sociodemographic variables including age, education, marital status, and household composition. In addition, respondents with reported vision impairment, stroke, and diabetes were at increased risk for cognitive decline after controlling for multiple potential confounders.
Although age and education have been reported as the more salient predictors of cognitive deterioration, other sociodemographic and several medical conditions including stroke and diabetes should be considered as part of cognitive aging studies among Mexican American elders.
本分析的目的是研究墨西哥裔美国老年人的社会人口统计学变量和健康相关状况与认知功能5年下降之间的关联。
1993/1994年和1998/1999年使用简易精神状态检查表（MMSE）对1759名参与者的认知功能进行了评估。认知功能下降由两组标准定义：（1）随访时MMSE评分降至17分或更低；（2）至少下降3分，即基线时得分在第5百分位数分布或以上的受访者MMSE评分的平均变化。
认知功能下降与年龄、教育程度、婚姻状况和家庭构成等社会人口统计学变量显著相关。此外，在控制了多个潜在混杂因素后，报告有视力障碍、中风和糖尿病的受访者认知功能下降的风险增加。
尽管年龄和教育程度被认为是认知功能恶化更显著的预测因素，但其他社会人口统计学因素以及包括中风和糖尿病在内的一些医疗状况应被视为墨西哥裔美国老年人认知老化研究的一部分。
