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化疗后伴严重食管狭窄的急性髓系白血病

[Acute myelogenous leukemia associated with severe esophageal stricture after chemotherapy].

作者信息

Yata Kenichiro, Yamada Osamu, Iwato Koji, Kyo Taiichi, Otsuki Takemi, Nakanishi Hidekazu, Suetsugu Yoshimasa, Mikami Makoto, Wada Hideho, Yawata Yoshihito, Sugihara Takashi

机构信息

Division of Hematology, Department of Medicine, Kawasaki Medical School.

出版信息

Rinsho Ketsueki. 2002 Jan;43(1):41-3.

Abstract

A 41-year-old woman with relapsed acute myelogenous leukemia was treated twice with idarubicin hydrochloride and cytarabine. She developed a 6-cm-long stricture in the lower esophagus 12 days after re-induction therapy. Although she had preceding candida infection, it is suspected that her stricture was caused by mucosal damage due to chemotherapeutic agents. This case suggests that the possibility of esophageal stricture should be considered in patients with swallowing disturbance after intensive chemotherapy.

摘要

一名41岁复发急性髓性白血病女性患者接受了两次盐酸伊达比星和阿糖胞苷治疗。再诱导治疗12天后,她的食管下段出现了一个6厘米长的狭窄。尽管她之前有念珠菌感染,但怀疑她的狭窄是由化疗药物引起的黏膜损伤所致。该病例提示,强化化疗后出现吞咽障碍的患者应考虑食管狭窄的可能性。

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