Sedhom Daniel, Sedhom Ramy, Mishra Avantika, Razjouyan Hadie, Rustgi Vinod
Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
ACG Case Rep J. 2017 Aug 16;4:e99. doi: 10.14309/crj.2017.99. eCollection 2017.
Although dysphagia in patients treated for malignancy is usually related to reflux esophagitis, infectious esophagitis, malignant infiltration, or as a complication of radiation therapy, acute esophageal stricture resulting from chemotherapy is very rare. Only 2 prior cases have been described in the treatment of an adult patient with malignancy. We present a unique case of isolated chemotherapy-induced esophageal stricture in a patient receiving treatment for metastatic testicular seminoma without prior history of gastroesophageal reflux disease, caustic ingestion, or other risk factors for esophageal stricture formation.
尽管接受恶性肿瘤治疗的患者出现吞咽困难通常与反流性食管炎、感染性食管炎、恶性浸润或作为放射治疗的并发症有关，但化疗导致的急性食管狭窄非常罕见。在成年恶性肿瘤患者的治疗中，此前仅报道过2例。我们报告了1例独特的孤立性化疗引起的食管狭窄病例，该患者正在接受转移性睾丸精原细胞瘤的治疗，既往无胃食管反流病、腐蚀性物质摄入或其他食管狭窄形成的危险因素。
