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获得性皮肤松弛症伴多发性骨髓瘤。

Acquired cutis laxa associated with multiple myeloma.

作者信息

Gupta Anjeli, Helm Thomas N

机构信息

State University of New York at Buffalo School of Medicine, USA.

出版信息

Cutis. 2002 Feb;69(2):114-8.

Abstract

Cutis laxa is an uncommon condition characterized by loose and redundant skin. Biopsy results are positive for a reduction in or an absence of elastic fibers in the dermis. Cutis laxa is acquired or congenital. The acquired form is either a generalized insidious form (type I) or a form associated with prior inflammation (type II). Cardiovascular, pulmonary, gastrointestinal, and urologic complications may occur. In the past, cutis laxa was associated with plasma cell dyscrasia. We report on a characteristic cause of cutis laxa to alert clinicians to this uncommon manifestation of multiple myeloma.

摘要

皮肤松弛症是一种罕见的疾病,其特征为皮肤松弛且多余。活检结果显示真皮中弹性纤维减少或缺失呈阳性。皮肤松弛症可后天获得或为先天性。后天获得型可为全身性隐匿型(I型)或与既往炎症相关型(II型)。可能会出现心血管、肺部、胃肠道和泌尿系统并发症。过去,皮肤松弛症与浆细胞异常增殖症有关。我们报告了一例皮肤松弛症的典型病因,以提醒临床医生注意这种多发性骨髓瘤的罕见表现。

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