Stieve H
Naturwissenschaften. 1975 Sep;62(9):425-33. doi: 10.1007/BF00612094.
Light snesory cells are sensitive photon-counting devices. The mechanism by which the light stimulus is transduced to nervous excitation is described. The absorption of a photon by the visual pigment-rhodopsin, a chromoprotein-causes a photo-chemical reaction, which is followed by a cascade of dark reactions of rhodopsin. One of these reactions triggers conductivity changes in the membrane of the visual cell, which results in a transient voltage impulse across the cell membrane. The magnitude and time course of this electrical signal contain the information of the light stimulus. The molecular mechanism of visual excitation can now be investigated experimentally.
光感受器细胞是灵敏的光子计数装置。本文描述了光刺激转化为神经兴奋的机制。视觉色素视紫红质(一种色蛋白)吸收一个光子会引发光化学反应,随后是视紫红质的一系列暗反应。其中一个反应触发视觉细胞膜的电导率变化,导致细胞膜上出现瞬时电压脉冲。这个电信号的幅度和时间进程包含了光刺激的信息。现在可以通过实验研究视觉兴奋的分子机制。