Waern Margda, Runeson Bo S, Allebeck Peter, Beskow Jan, Rubenowitz Eva, Skoog Ingmar, Wilhelmsson Katarina
Section of Psychiatry, Institute of Clinical Neuroscience and Department of Social Medicine, Göteborg University, Sweden.
Am J Psychiatry. 2002 Mar;159(3):450-5. doi: 10.1176/appi.ajp.159.3.450.
The authors' goal was to study the importance of different psychiatric disorders in relation to suicide in individuals 65 years old or older.
The psychological autopsy approach was used to study 85 cases of suicide among subjects who were 65 years old or older; 153 living comparison subjects from the same age group who were randomly selected from the tax register were interviewed face-to-face. Retrospective axis I diagnoses were made according to DSM-IV on the basis of interview data and medical records.
Ninety-seven percent of the suicide victims fulfilled criteria for at least one DSM-IV axis I diagnosis, compared with 18% of the living comparison subjects. Recurrent major depressive disorder was a very strong risk factor for suicide, as was substance use disorder. An elevated risk was also associated with minor depressive disorder, dysthymic disorder, psychotic disorder, single-episode major depressive disorder, and anxiety disorder. Comorbid axis I disorders were observed in 15 (38%) of the 39 elderly subjects with major depressive disorder who had committed suicide.
Although recurrent major depressive disorder was the mental disorder most strongly associated with suicide, the findings of this study suggest that elderly individuals who commit suicide represent a heterogeneous group with regard to mental disorders, implying a need for differentiated prevention strategies.
作者旨在研究65岁及以上个体中不同精神障碍与自杀的相关性。
采用心理解剖学方法研究85例65岁及以上自杀者;从税务登记册中随机抽取153名同年龄组的在世对照者进行面对面访谈。根据访谈数据和病历,依据《精神疾病诊断与统计手册》第四版(DSM-IV)做出回顾性轴I诊断。
97%的自杀受害者符合至少一项DSM-IV轴I诊断标准,而在世对照者中这一比例为18%。复发性重度抑郁症是自杀的一个非常强的危险因素,物质使用障碍也是如此。轻度抑郁症、恶劣心境障碍、精神障碍、单次发作重度抑郁症和焦虑症也与自杀风险升高有关。在39例自杀的患有重度抑郁症的老年受试者中,有15例(38%)存在共病轴I障碍。
虽然复发性重度抑郁症是与自杀关联最密切的精神障碍,但本研究结果表明,自杀的老年人在精神障碍方面是一个异质性群体,这意味着需要采取差异化的预防策略。