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[Treatment of acute experimental diphtheria toxemia by immunohemosorption].

作者信息

Kuznetsov S I, Barashkova L N, Nosikova E V, Korosteleva Iu G, Kanaev P A, Burkova N V, Eĭsmont Iu A, Tiukavin A I

出版信息

Patol Fiziol Eksp Ter. 2001 Oct-Dec(4):10-2.

Abstract

The antitoxic antidiphtheric immunosorbent DATs was tested in experiments on mice and guinea-pigs using the model of acute diphtheric toxemia. In extracorporeal connecting with the circulation system of the animals the sorbent effectively bound and eliminated from the circulation molecules of diphtheric toxin and antitoxin, reduced significantly their levels in the blood after hemoperfusion. The effectiveness of the immunosorbent DATs was confirmed when it saved the ginea-pigs after injection of lethal toxin doses.

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