Bul'on V V, Khnychenko L K, Sapronov N S, Kuznetsova N N, Anikin V B, arinenko R Iu, Kovalenko A L, Alekseeva L E
Department of Neuropharmacology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, ul. Akademika Pavlova 12, St. Petersburg, 197376 Russia.
Eksp Klin Farmakol. 2001 Nov-Dec;64(6):41-4.
The possibility of using cycloferon (interferon inductor) for a complex treatment (in combination with the main drug solcoseryl possessing pronounced therapeutic properties) of duodenum ulcers was experimentally studied in male rats. The experiments showed a considerable difference in the interferon status of animals with model duodenum ulcers treated with cycloferon, solcoseryl, their combination, and placebo (control). The healing effect of solcoseryl administered in combination with cycloferon exceeded that of each component administered separately.
在雄性大鼠身上进行了实验研究,探讨使用环孢菌素(干扰素诱导剂)对十二指肠溃疡进行综合治疗(与具有显著治疗特性的主要药物索高捷疗联合使用)的可能性。实验表明,用环孢菌素、索高捷疗、二者联合用药以及安慰剂(对照)治疗的患有十二指肠溃疡模型的动物,其干扰素状态存在显著差异。索高捷疗与环孢菌素联合使用的愈合效果超过了单独使用每种成分的效果。