Mamikoglu Bulent, Wiet Richard J, Esquivel Carlos R
Division of Otolaryngology, Northwestern University Medical School, Evanston Hospital, Evanston Northwestern Health Care System, Evanston, Illinois 60201, USA.
Otol Neurotol. 2002 Mar;23(2):224-7. doi: 10.1097/00129492-200203000-00020.
The removal of large vestibular schwannomas through the translabyrinthine approach is still controversial.
A retrospective review was performed of 81 patients (58 men and 23 women) with vestibular schwannomas 3 cm or greater, who underwent tumor removal via the translabyrinthine approach between 1985 and 2000. The mean tumor size was 3.7 +/- 0.81 cm, and the mean age of the patients was 47 +/- 16.1 years. The largest tumor was 6 cm. All surgical procedures were performed in collaboration with a neurosurgery team.
Total tumor removal was accomplished in 77 cases (95.1%). The facial nerve was preserved anatomically in 69 (85.2%) of the patients. In 4 patients, divided nerves were repaired by primary anastomosis. Facial nerve function was assessed immediately after surgery and 1 year or more after discharge. Good function (House-Brackmann facial nerve Grade I or II) was present in 45% of patients and acceptable function (Grades I-IV) in 80% of patients 1 year after resection of the tumor. Cerebrospinal fluid leakage occurred in 12 patients (17%), meningitis developed in 3 patients (4%), and 1 patient experienced a stroke immediately after surgery. There were no deaths caused by surgery in this series.
The translabyrinthine approach offers an excellent anatomical view of the cerebellopontine angle and a direct approach to the tumor with functional preservation of the facial nerve. Total removal is accomplished in most cases, with minimum incidence of morbidity and no incidence of mortality.
通过经迷路入路切除大型前庭神经鞘瘤仍存在争议。
对1985年至2000年间81例(58例男性和23例女性)患有3厘米或更大前庭神经鞘瘤的患者进行回顾性研究,这些患者通过经迷路入路进行肿瘤切除。肿瘤平均大小为3.7 +/- 0.81厘米,患者平均年龄为47 +/- 16.1岁。最大肿瘤为6厘米。所有手术均与神经外科团队合作进行。
77例(95.1%)实现了肿瘤全切。69例(85.2%)患者的面神经在解剖学上得以保留。4例患者的离断神经通过一期吻合进行修复。术后立即以及出院后1年或更长时间对面神经功能进行评估。肿瘤切除术后1年,45%的患者面神经功能良好(House-Brackmann面神经分级I级或II级),80%的患者面神经功能可接受(分级I-IV级)。12例患者(17%)发生脑脊液漏,3例患者(4%)发生脑膜炎,1例患者术后立即发生中风。本系列中无手术死亡病例。
经迷路入路能提供极佳的桥小脑角解剖视野,可直接到达肿瘤,并对面神经进行功能保留。大多数情况下可实现全切,发病率极低,无死亡病例。