Mapletoft R J, Del Campo M R, Ginther O J
Proc Soc Exp Biol Med. 1975 Oct;150(1):129-33. doi: 10.3181/00379727-150-38988.
The involvement of the main uterine vein in the unilateral maintenance of CL was studied in bilaterally ovulating unilaterally pregnant ewes. Ewes were mated at estrus (Day 0) and bilaterally ovulating ewes were randomized into three groups at surgery on Day 5. In all ewes, the uterine horns were separated through the intercornual area and one was ligated and transected near the internal bifurcation to produce a nongravid horn. One group served as controls (five ewes). In the other two groups the main uterine vein on one side was surgically anastomosed (end to side) to the corresponding vein of the opposite side (gravid side to nongravid side in one group--three ewes, and nongravid side to gravid side in the other--three ewes). Necropsies were done on Day 20. Mean CL weight was less, (P less than .01) on the nongravid side in control ewes than on the gravid side in control ewes or for either side in the other two groups. There were no significant differences among mean weights of CL on the gravid side in control ewes and either side in the other two groups. The CL regressed when the ipsilateral uterine vein contained blood from only the nongravid horn whereas the CL was maintained when the ipsilateral uterine vein contained venous blood from a gravid horn, whether or not it also contained blood from a nongravid horn. Results indicate that the uterine venous effluent from a gravid uterine horn in sheep has a luteotropic effect on the ipsilateral CL.
在双侧排卵但单侧怀孕的母羊中，研究了子宫主静脉在黄体单侧维持中的作用。母羊在发情期（第0天）交配，双侧排卵的母羊在第5天手术时随机分为三组。在所有母羊中，子宫角通过角间区域分离，其中一个在靠近内部分叉处结扎并横断以形成非妊娠角。一组作为对照（五只母羊）。在另外两组中，一侧的子宫主静脉通过手术与另一侧相应的静脉进行端侧吻合（一组中妊娠侧与非妊娠侧吻合——三只母羊，另一组中非妊娠侧与妊娠侧吻合——三只母羊）。在第20天进行尸检。对照母羊中非妊娠侧的平均黄体重量低于对照母羊中妊娠侧的平均黄体重量，也低于另外两组中任一侧的平均黄体重量（P<0.01）。对照母羊中妊娠侧的黄体平均重量与另外两组中任一侧的黄体平均重量之间没有显著差异。当同侧子宫静脉仅含有来自非妊娠角的血液时，黄体退化；而当同侧子宫静脉含有来自妊娠角的静脉血时，黄体得以维持，无论它是否也含有来自非妊娠角的血液。结果表明，绵羊妊娠子宫角的子宫静脉流出物对同侧黄体具有促黄体作用。
