Li S, Cai K, Sun N, Wang Z, Xia Q
Radiology Department, Beijing Hospital, Beijing 100730.
Zhonghua Yan Ke Za Zhi. 1998 Nov;34(6):441-3, 27.
To clarify the characteristic magnetic resonance imaging (MRI) features of choroidal melanomas by the high field MRI to improve the accuracy of diagnosis and localization and to differentiate choroidal melanomas from other choroidal lesions.
12 patients with choroidal melanomas were examined by GE 1.5T magnet and heat coil, fat suppression technique and GD-DPTA as contrast agent were also used. Ten patients underwent operations and the histopathologic diagnosis was confirmed.
The melanomas of the 12 patients had relatively high signals on T(1) weighted image and relatively low signals on T(2) weighted image. This is because of the paramagnetic properties of melanin. The melanomas with melanin can produce stable free radicals, both T(1) and T(2) relaxation times are shortened, with this we can differentiate melanomas from other choroidal lesions.
Sagittal, coronal, axial and oblique scanning with small feild of view for the orbit by MRI can be made to show the exact position of melanomas and differentiate them from other choroidal lesions.
通过高场磁共振成像(MRI)明确脉络膜黑色素瘤的特征性MRI表现,以提高诊断和定位的准确性,并将脉络膜黑色素瘤与其他脉络膜病变区分开来。
采用GE 1.5T磁体和热线圈对12例脉络膜黑色素瘤患者进行检查,同时使用脂肪抑制技术和GD-DPTA作为对比剂。10例患者接受了手术,病理诊断得到证实。
12例患者的黑色素瘤在T(1)加权图像上信号相对较高,在T(2)加权图像上信号相对较低。这是由于黑色素的顺磁性质。含有黑色素的黑色素瘤可产生稳定的自由基,T(1)和T(2)弛豫时间均缩短,借此可将黑色素瘤与其他脉络膜病变区分开来。
通过MRI对眼眶进行小视野的矢状、冠状、轴位和斜位扫描,可显示黑色素瘤的确切位置,并将其与其他脉络膜病变区分开来。