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[孕早期颈部透明带测量后1252例胎儿的妊娠结局]

[Pregnancy outcome in 1,252 fetuses after nuchal translucency measurement in the 1st trimester].

作者信息

Horner E, Holzgreve W, Batucan C, Tercanli S

机构信息

Universitäts-Frauenklink, Basel.

出版信息

Praxis (Bern 1994). 2002 Feb 13;91(7):261-5. doi: 10.1024/0369-8394.91.7.261.

Abstract

The measurement of the nuchal translucency is an important marker to detect a vast number of fetal anomalies. Lately the nuchal translucency has been used increasingly as a screening method to find chromosomal anomalies especially for trisomy 21. Beside a high incidence of chromosomal defects one assumes a high risk of rare syndromes and other associated anomalies such as heart defects, skeletal anomalies, cerebral anomalies, diaphragmatic hernias, as well as of an intrauterine death. In view of abortion rate, detection rate of chromosomal anomalies, other fetal anomalies and rare syndromes we evaluated in this study the pregnancy outcome after nuchal translucency measurement, and discuss a concept for its management.

摘要

颈部半透明厚度的测量是检测大量胎儿异常的重要指标。最近,颈部半透明厚度越来越多地被用作一种筛查方法,以发现染色体异常,尤其是21三体综合征。除了染色体缺陷的高发生率外,人们还认为存在罕见综合征和其他相关异常的高风险,如心脏缺陷、骨骼异常、脑部异常、膈疝以及宫内死亡。鉴于流产率、染色体异常的检出率、其他胎儿异常和罕见综合征,我们在本研究中评估了颈部半透明厚度测量后的妊娠结局,并讨论了其管理概念。

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