XYY个体的睾酮生成

Testosterone production by XYY subjects.

作者信息

Sharma M, Meyer-Bahlburg H F, Boon D A, Slaunwhite W R, Edwards J A

出版信息

Steroids. 1975 Aug;26(2):175-80. doi: 10.1016/s0039-128x(75)80018-3.

Abstract

A study of plasma concentration (P1T, ng/ml), metabolic clearance rate (MCRT, L/day) and blood production rate (PBT, mg/day) was done on seven XYY subjects of various ages and four pair-matched control XY subjects by a radioinfusion technique of 1,2-3H-testosterone. Although MCRT showed no significant difference between the groups, P1T and PBT were significantly lower (P less than 0.05) in XYY subjects. Therefore, increased aggressive behavior of the XYY subjects can not be attributed to increased levels or production rates of testosterone.

摘要

通过1,2 - 3H - 睾酮的放射性输注技术，对7名不同年龄的XYY男性受试者和4名配对的XY对照男性受试者进行了血浆浓度（P1T，纳克/毫升）、代谢清除率（MCRT，升/天）和血液生成率（PBT，毫克/天）的研究。虽然两组之间的MCRT没有显著差异，但XYY受试者的P1T和PBT显著较低（P小于0.05）。因此，XYY受试者攻击性行为增加不能归因于睾酮水平或生成率的提高。