脑膜炎奈瑟菌的基因组学

Genomics of Neisseria meningitidis.

作者信息

Nassif Xavier

机构信息

INSERM U411, Faculté de Médecine Necker-Enfants Malades, Université René Descartes, Paris, France.

出版信息

Int J Med Microbiol. 2002 Feb;291(6-7):419-23. doi: 10.1078/1438-4221-00148.

DOI:10.1078/1438-4221-00148

PMID:11890539

Abstract

An important feature of disease caused by Neisseria meningitidis is the propensity to invade the meninges. Much progress has been made in our understanding of how this pathogen circumvents the physical properties of this cellular barrier. This review will address the new possibilities offered by the recent availability of meningococcal genome sequences.

摘要

脑膜炎奈瑟菌引起的疾病的一个重要特征是易于侵袭脑膜。在我们理解这种病原体如何规避这种细胞屏障的物理特性方面已经取得了很大进展。本综述将探讨脑膜炎球菌基因组序列近期可得所带来的新可能性。